Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 379.4 BDBM24283

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24283 ((2S)-2-amino-4-({4-[4-(1H-pyrrol-1-yl)phenoxy]phen...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(Oc2ccc(cc2)-n2cccc2)cc1)C(O)=O |r| Show InChI InChI=1S/C21H21N3O4/c22-19(21(26)27)11-12-20(25)23-15-3-7-17(8-4-15)28-18-9-5-16(6-10-18)24-13-1-2-14-24/h1-10,13-14,19H,11-12,22H2,(H,23,25)(H,26,27)/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
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