Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 429.4 BDBM24298

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24298 ((4S)-4-amino-5-(1,3-dioxo-2,3-dihydro-1H-isoindol-...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(Oc2ccccc2)cc1)CN1C(=O)c2ccccc2C1=O |r| Show InChI InChI=1S/C25H23N3O4/c26-17(16-28-24(30)21-8-4-5-9-22(21)25(28)31)10-15-23(29)27-18-11-13-20(14-12-18)32-19-6-2-1-3-7-19/h1-9,11-14,17H,10,15-16,26H2,(H,27,29)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
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