Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 349.4 BDBM24297

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24297 ((4S)-4-amino-N-(4-phenoxyphenyl)-5-(1H-pyrrol-1-yl...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(Oc2ccccc2)cc1)Cn1cccc1 |r| Show InChI InChI=1S/C21H23N3O2/c22-17(16-24-14-4-5-15-24)8-13-21(25)23-18-9-11-20(12-10-18)26-19-6-2-1-3-7-19/h1-7,9-12,14-15,17H,8,13,16,22H2,(H,23,25)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
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