Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 337.3 BDBM24295

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24295 ((4S)-4-amino-N-(4-phenoxyphenyl)-4-(4H-1,2,4-triaz...) Show SMILES N[C@@H](CCC(=O)Nc1ccc(Oc2ccccc2)cc1)c1nnc[nH]1 |r| Show InChI InChI=1S/C18H19N5O2/c19-16(18-20-12-21-23-18)10-11-17(24)22-13-6-8-15(9-7-13)25-14-4-2-1-3-5-14/h1-9,12,16H,10-11,19H2,(H,22,24)(H,20,21,23)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
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