Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 391.4 BDBM50046321

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50046321 (3-Amino-4-(4-benzyloxy-phenyl)-2-hydroxy-butyric a...) Show SMILES N[C@@H](Cc1ccc(OCc2ccccc2)cc1)[C@H](O)C(=O)OCc1ccccc1 Show InChI InChI=1S/C24H25NO4/c25-22(23(26)24(27)29-17-20-9-5-2-6-10-20)15-18-11-13-21(14-12-18)28-16-19-7-3-1-4-8-19/h1-14,22-23,26H,15-17,25H2/t22-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytes				J Med Chem 36: 211-20 (1993) BindingDB Entry DOI: 10.7270/Q2T152P3
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Homo sapiens (Human))	BDBM50046321 (3-Amino-4-(4-benzyloxy-phenyl)-2-hydroxy-butyric a...) Show SMILES N[C@@H](Cc1ccc(OCc2ccccc2)cc1)[C@H](O)C(=O)OCc1ccccc1 Show InChI InChI=1S/C24H25NO4/c25-22(23(26)24(27)29-17-20-9-5-2-6-10-20)15-18-11-13-21(14-12-18)28-16-19-7-3-1-4-8-19/h1-14,22-23,26H,15-17,25H2/t22-,23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration against cytosolic leucine aminopeptidase				J Med Chem 36: 211-20 (1993) BindingDB Entry DOI: 10.7270/Q2T152P3
					More data for this Ligand-Target Pair
Leucyl-cystinyl aminopeptidase (Rattus norvegicus)	BDBM50046321 (3-Amino-4-(4-benzyloxy-phenyl)-2-hydroxy-butyric a...) Show SMILES N[C@@H](Cc1ccc(OCc2ccccc2)cc1)[C@H](O)C(=O)OCc1ccccc1 Show InChI InChI=1S/C24H25NO4/c25-22(23(26)24(27)29-17-20-9-5-2-6-10-20)15-18-11-13-21(14-12-18)28-16-19-7-3-1-4-8-19/h1-14,22-23,26H,15-17,25H2/t22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration against aminopeptidase M				J Med Chem 36: 211-20 (1993) BindingDB Entry DOI: 10.7270/Q2T152P3
					More data for this Ligand-Target Pair