Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM454550
(US10717746, Example 31b)Show SMILES N[C@@H]1CCC[C@@H](C1)C(=O)Nc1cc(-c2cnn3CCCCc23)c(Cl)cn1 |r| Show InChI InChI=1S/C19H24ClN5O/c20-16-11-22-18(24-19(26)12-4-3-5-13(21)8-12)9-14(16)15-10-23-25-7-2-1-6-17(15)25/h9-13H,1-8,21H2,(H,22,24,26)/t12-,13+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
ASTRAZENECA AB
US Patent
| Assay Description Activity of CDK9 was determined in-vitro using a mobility shift assay on a Caliper LC3000 reader (Caliper/PerkinElmer), which measures fluorescence o... |
US Patent US10717746 (2020)
BindingDB Entry DOI: 10.7270/Q2NV9N9F |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM454550
(US10717746, Example 31b)Show SMILES N[C@@H]1CCC[C@@H](C1)C(=O)Nc1cc(-c2cnn3CCCCc23)c(Cl)cn1 |r| Show InChI InChI=1S/C19H24ClN5O/c20-16-11-22-18(24-19(26)12-4-3-5-13(21)8-12)9-14(16)15-10-23-25-7-2-1-6-17(15)25/h9-13H,1-8,21H2,(H,22,24,26)/t12-,13+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 2.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ASTRAZENECA AB
US Patent
| Assay Description Activity of CDK9 was determined in-vitro using a mobility shift assay on a Caliper LC3000 reader (Caliper/PerkinElmer), which measures fluorescence o... |
US Patent US10717746 (2020)
BindingDB Entry DOI: 10.7270/Q2NV9N9F |
More data for this Ligand-Target Pair | |