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Compile Data Set for Download or QSAR

Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 331.2
BDBM50062538

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50062538
PNG
((S)-2-[(R)-1-Amino-1-carboxy-3-(3-trifluoromethyl-...)
Show SMILES N[C@](CCc1cccc(c1)C(F)(F)F)(C1C[C@@H]1C(O)=O)C(O)=O
Show InChI InChI=1S/C15H16F3NO4/c16-15(17,18)9-3-1-2-8(6-9)4-5-14(19,13(22)23)11-7-10(11)12(20)21/h1-3,6,10-11H,4-5,7,19H2,(H,20,21)(H,22,23)/t10-,11?,14+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 220n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Effect on 1S,3R-ACPD-induced inhibition of forskolin stimulated cyclic-AMP in RGT cells expressing human Metabotropic glutamate receptor 2


J Med Chem 41: 358-78 (1998)


Article DOI: 10.1021/jm970498o
BindingDB Entry DOI: 10.7270/Q2XP7423
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Homo sapiens (Human))
BDBM50062538
PNG
((S)-2-[(R)-1-Amino-1-carboxy-3-(3-trifluoromethyl-...)
Show SMILES N[C@](CCc1cccc(c1)C(F)(F)F)(C1C[C@@H]1C(O)=O)C(O)=O
Show InChI InChI=1S/C15H16F3NO4/c16-15(17,18)9-3-1-2-8(6-9)4-5-14(19,13(22)23)11-7-10(11)12(20)21/h1-3,6,10-11H,4-5,7,19H2,(H,20,21)(H,22,23)/t10-,11?,14+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 420n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Effect on 1S,3R-ACPD-induced inhibition of forskolin stimulated cyclic-AMP in RGT cells expressing human Metabotropic glutamate receptor 3


J Med Chem 41: 358-78 (1998)


Article DOI: 10.1021/jm970498o
BindingDB Entry DOI: 10.7270/Q2XP7423
More data for this
Ligand-Target Pair