Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50062538
((S)-2-[(R)-1-Amino-1-carboxy-3-(3-trifluoromethyl-...)Show SMILES N[C@](CCc1cccc(c1)C(F)(F)F)(C1C[C@@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C15H16F3NO4/c16-15(17,18)9-3-1-2-8(6-9)4-5-14(19,13(22)23)11-7-10(11)12(20)21/h1-3,6,10-11H,4-5,7,19H2,(H,20,21)(H,22,23)/t10-,11?,14+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Effect on 1S,3R-ACPD-induced inhibition of forskolin stimulated cyclic-AMP in RGT cells expressing human Metabotropic glutamate receptor 2 |
J Med Chem 41: 358-78 (1998)
Article DOI: 10.1021/jm970498o BindingDB Entry DOI: 10.7270/Q2XP7423 |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 3
(Homo sapiens (Human)) | BDBM50062538
((S)-2-[(R)-1-Amino-1-carboxy-3-(3-trifluoromethyl-...)Show SMILES N[C@](CCc1cccc(c1)C(F)(F)F)(C1C[C@@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C15H16F3NO4/c16-15(17,18)9-3-1-2-8(6-9)4-5-14(19,13(22)23)11-7-10(11)12(20)21/h1-3,6,10-11H,4-5,7,19H2,(H,20,21)(H,22,23)/t10-,11?,14+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Effect on 1S,3R-ACPD-induced inhibition of forskolin stimulated cyclic-AMP in RGT cells expressing human Metabotropic glutamate receptor 3 |
J Med Chem 41: 358-78 (1998)
Article DOI: 10.1021/jm970498o BindingDB Entry DOI: 10.7270/Q2XP7423 |
More data for this Ligand-Target Pair | |