Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Methionine aminopeptidase 2
(Homo sapiens (Human)) | BDBM50141726
(3-Amino-4-cyclohexyl-2-(S)-hydroxy-N-((R)-2-hydrox...)Show SMILES N[C@H](CC1CCCCC1)[C@H](O)C(=O)N[C@@H](CO)c1ccccc1 Show InChI InChI=1S/C18H28N2O3/c19-15(11-13-7-3-1-4-8-13)17(22)18(23)20-16(12-21)14-9-5-2-6-10-14/h2,5-6,9-10,13,15-17,21-22H,1,3-4,7-8,11-12,19H2,(H,20,23)/t15-,16+,17+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibitory activity against human methionine aminopeptidase-2 |
Bioorg Med Chem Lett 14: 865-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.031 BindingDB Entry DOI: 10.7270/Q2Z31Z3N |
More data for this Ligand-Target Pair | |
Methionine aminopeptidase 1
(Homo sapiens (Human)) | BDBM50141726
(3-Amino-4-cyclohexyl-2-(S)-hydroxy-N-((R)-2-hydrox...)Show SMILES N[C@H](CC1CCCCC1)[C@H](O)C(=O)N[C@@H](CO)c1ccccc1 Show InChI InChI=1S/C18H28N2O3/c19-15(11-13-7-3-1-4-8-13)17(22)18(23)20-16(12-21)14-9-5-2-6-10-14/h2,5-6,9-10,13,15-17,21-22H,1,3-4,7-8,11-12,19H2,(H,20,23)/t15-,16+,17+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibitory activity against human methionine aminopeptidase-1 |
Bioorg Med Chem Lett 14: 865-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.031 BindingDB Entry DOI: 10.7270/Q2Z31Z3N |
More data for this Ligand-Target Pair | |