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Compile Data Set for Download or QSAR

Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 320.4
BDBM50141726

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine aminopeptidase 2


(Homo sapiens (Human))
BDBM50141726
PNG
(3-Amino-4-cyclohexyl-2-(S)-hydroxy-N-((R)-2-hydrox...)
Show SMILES N[C@H](CC1CCCCC1)[C@H](O)C(=O)N[C@@H](CO)c1ccccc1
Show InChI InChI=1S/C18H28N2O3/c19-15(11-13-7-3-1-4-8-13)17(22)18(23)20-16(12-21)14-9-5-2-6-10-14/h2,5-6,9-10,13,15-17,21-22H,1,3-4,7-8,11-12,19H2,(H,20,23)/t15-,16+,17+/m1/s1
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 120n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against human methionine aminopeptidase-2


Bioorg Med Chem Lett 14: 865-8 (2004)


Article DOI: 10.1016/j.bmcl.2003.12.031
BindingDB Entry DOI: 10.7270/Q2Z31Z3N
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Homo sapiens (Human))
BDBM50141726
PNG
(3-Amino-4-cyclohexyl-2-(S)-hydroxy-N-((R)-2-hydrox...)
Show SMILES N[C@H](CC1CCCCC1)[C@H](O)C(=O)N[C@@H](CO)c1ccccc1
Show InChI InChI=1S/C18H28N2O3/c19-15(11-13-7-3-1-4-8-13)17(22)18(23)20-16(12-21)14-9-5-2-6-10-14/h2,5-6,9-10,13,15-17,21-22H,1,3-4,7-8,11-12,19H2,(H,20,23)/t15-,16+,17+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.80E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against human methionine aminopeptidase-1


Bioorg Med Chem Lett 14: 865-8 (2004)


Article DOI: 10.1016/j.bmcl.2003.12.031
BindingDB Entry DOI: 10.7270/Q2Z31Z3N
More data for this
Ligand-Target Pair