Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50397949
(CHEMBL2179973)Show SMILES N[C@H]1CCc2ccccc2[C@@H](CCCc2ccccc2)C1=O |r| Show InChI InChI=1S/C20H23NO/c21-19-14-13-16-10-4-5-11-17(16)18(20(19)22)12-6-9-15-7-2-1-3-8-15/h1-5,7-8,10-11,18-19H,6,9,12-14,21H2/t18-,19+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Haute Alsace
Curated by ChEMBL
| Assay Description Competitive inhibition of pig APN using L-leucine-p-nitroanilide as substrate by Dixon-plot analysis |
Bioorg Med Chem 20: 4942-53 (2012)
Article DOI: 10.1016/j.bmc.2012.06.041 BindingDB Entry DOI: 10.7270/Q2RB75Q1 |
More data for this Ligand-Target Pair | |
Cytosol aminopeptidase
(Bos taurus (bovine)) | BDBM50397949
(CHEMBL2179973)Show SMILES N[C@H]1CCc2ccccc2[C@@H](CCCc2ccccc2)C1=O |r| Show InChI InChI=1S/C20H23NO/c21-19-14-13-16-10-4-5-11-17(16)18(20(19)22)12-6-9-15-7-2-1-3-8-15/h1-5,7-8,10-11,18-19H,6,9,12-14,21H2/t18-,19+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Haute Alsace
Curated by ChEMBL
| Assay Description Competitive inhibition of bovine LAPc using L-leucine-p-nitroanilide as substrate by spectrophotometric analysis |
Bioorg Med Chem 20: 4942-53 (2012)
Article DOI: 10.1016/j.bmc.2012.06.041 BindingDB Entry DOI: 10.7270/Q2RB75Q1 |
More data for this Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50397949
(CHEMBL2179973)Show SMILES N[C@H]1CCc2ccccc2[C@@H](CCCc2ccccc2)C1=O |r| Show InChI InChI=1S/C20H23NO/c21-19-14-13-16-10-4-5-11-17(16)18(20(19)22)12-6-9-15-7-2-1-3-8-15/h1-5,7-8,10-11,18-19H,6,9,12-14,21H2/t18-,19+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Haute Alsace
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant LTA4H using alanine-p-nitroanilide as substrate by spectrophootmetric analysis |
Bioorg Med Chem 20: 4942-53 (2012)
Article DOI: 10.1016/j.bmc.2012.06.041 BindingDB Entry DOI: 10.7270/Q2RB75Q1 |
More data for this Ligand-Target Pair | |