Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prothrombin
(Homo sapiens (Human)) | BDBM50290020
((S)-1-Phenylacetyl-pyrrolidine-2-carboxylic acid (...)Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)Cc1ccccc1)C=O Show InChI InChI=1S/C19H27N5O3/c20-19(21)22-10-4-8-15(13-25)23-18(27)16-9-5-11-24(16)17(26)12-14-6-2-1-3-7-14/h1-3,6-7,13,15-16H,4-5,8-12H2,(H,23,27)(H4,20,21,22)/t15-,16-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In vitro ability to inhibit the activity of human alpha Thrombin |
Bioorg Med Chem Lett 7: 2205-2210 (1997)
Article DOI: 10.1016/S0960-894X(97)00403-4 BindingDB Entry DOI: 10.7270/Q21G0MR2 |
More data for this Ligand-Target Pair | |
Serine protease 1
(Bos taurus (bovine)) | BDBM50290020
((S)-1-Phenylacetyl-pyrrolidine-2-carboxylic acid (...)Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)Cc1ccccc1)C=O Show InChI InChI=1S/C19H27N5O3/c20-19(21)22-10-4-8-15(13-25)23-18(27)16-9-5-11-24(16)17(26)12-14-6-2-1-3-7-14/h1-3,6-7,13,15-16H,4-5,8-12H2,(H,23,27)(H4,20,21,22)/t15-,16-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In vitro ability to inhibit the activity of Trypsin |
Bioorg Med Chem Lett 7: 2205-2210 (1997)
Article DOI: 10.1016/S0960-894X(97)00403-4 BindingDB Entry DOI: 10.7270/Q21G0MR2 |
More data for this Ligand-Target Pair | |
Plasminogen
(Homo sapiens (Human)) | BDBM50290020
((S)-1-Phenylacetyl-pyrrolidine-2-carboxylic acid (...)Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)Cc1ccccc1)C=O Show InChI InChI=1S/C19H27N5O3/c20-19(21)22-10-4-8-15(13-25)23-18(27)16-9-5-11-24(16)17(26)12-14-6-2-1-3-7-14/h1-3,6-7,13,15-16H,4-5,8-12H2,(H,23,27)(H4,20,21,22)/t15-,16-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 4.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In vitro ability to inhibit the activity of Plasmin |
Bioorg Med Chem Lett 7: 2205-2210 (1997)
Article DOI: 10.1016/S0960-894X(97)00403-4 BindingDB Entry DOI: 10.7270/Q21G0MR2 |
More data for this Ligand-Target Pair | |