Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Polyamine oxidase 1
(Zea mays) | BDBM50032500
(1,1'-(8,8'-azanediylbis(octane-8,1-diyl))diguanidi...)Show InChI InChI=1S/C18H41N7/c19-17(20)24-15-11-7-3-1-5-9-13-23-14-10-6-2-4-8-12-16-25-18(21)22/h23H,1-16H2,(H4,19,20,24)(H4,21,22,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
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CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| MMDB PDB Article PubMed
| 7.5 | n/a | n/a | n/a | n/a | n/a | n/a | 6.5 | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description Inhibition of maize PAO at pH 6.5 by spectrophotometry-based Dixon plot method |
J Med Chem 52: 4774-85 (2009)
Article DOI: 10.1021/jm900371z BindingDB Entry DOI: 10.7270/Q2TB16W1 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Deoxyhypusine synthase
(Rattus norvegicus) | BDBM50032500
(1,1'-(8,8'-azanediylbis(octane-8,1-diyl))diguanidi...)Show InChI InChI=1S/C18H41N7/c19-17(20)24-15-11-7-3-1-5-9-13-23-14-10-6-2-4-8-12-16-25-18(21)22/h23H,1-16H2,(H4,19,20,24)(H4,21,22,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Dental Research
Curated by ChEMBL
| Assay Description In vitro IC50 value by measuring the inhibition of deoxyhypusine synthase. |
J Med Chem 38: 3053-61 (1995)
BindingDB Entry DOI: 10.7270/Q2P55MJ2 |
More data for this Ligand-Target Pair | |