Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Serine protease 1
(Rattus norvegicus) | BDBM98587
((2R)-N-[(1S)-1-(benzyloxymethyl)-2-[(4-carbamimido...)Show SMILES NC(=N)c1ccc(CNC(=O)[C@H](COCc2ccccc2)NC(=O)[C@@H](CO)NS(=O)(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C28H33N5O6S/c29-26(30)23-13-11-20(12-14-23)15-31-27(35)25(18-39-17-21-7-3-1-4-8-21)32-28(36)24(16-34)33-40(37,38)19-22-9-5-2-6-10-22/h1-14,24-25,33-34H,15-19H2,(H3,29,30)(H,31,35)(H,32,36)/t24-,25+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| MMDB PC cid PC sid PDB UniChem
Similars
| US Patent
| 6.80 | -46.5 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company
US Patent
| Assay Description Inhibition constant of the compound against Trypsin |
US Patent US8476306 (2013)
BindingDB Entry DOI: 10.7270/Q2154FPH |
More data for this Ligand-Target Pair | |
Urokinase plasminogen activator surface receptor
(Rattus norvegicus) | BDBM98587
((2R)-N-[(1S)-1-(benzyloxymethyl)-2-[(4-carbamimido...)Show SMILES NC(=N)c1ccc(CNC(=O)[C@H](COCc2ccccc2)NC(=O)[C@@H](CO)NS(=O)(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C28H33N5O6S/c29-26(30)23-13-11-20(12-14-23)15-31-27(35)25(18-39-17-21-7-3-1-4-8-21)32-28(36)24(16-34)33-40(37,38)19-22-9-5-2-6-10-22/h1-14,24-25,33-34H,15-19H2,(H3,29,30)(H,31,35)(H,32,36)/t24-,25+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| MMDB PC cid PC sid PDB UniChem
Similars
| US Patent
| 28 | -43.0 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company
US Patent
| Assay Description Inhibition constant of the compound against Plasminogen activator urokinase |
US Patent US8476306 (2013)
BindingDB Entry DOI: 10.7270/Q2154FPH |
More data for this Ligand-Target Pair | |
Plasminogen
(Rattus norvegicus) | BDBM98587
((2R)-N-[(1S)-1-(benzyloxymethyl)-2-[(4-carbamimido...)Show SMILES NC(=N)c1ccc(CNC(=O)[C@H](COCc2ccccc2)NC(=O)[C@@H](CO)NS(=O)(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C28H33N5O6S/c29-26(30)23-13-11-20(12-14-23)15-31-27(35)25(18-39-17-21-7-3-1-4-8-21)32-28(36)24(16-34)33-40(37,38)19-22-9-5-2-6-10-22/h1-14,24-25,33-34H,15-19H2,(H3,29,30)(H,31,35)(H,32,36)/t24-,25+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| MMDB PC cid PC sid PDB UniChem
Similars
| US Patent
| 270 | -37.4 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company
US Patent
| Assay Description Inhibition constant of the compound against Plasmin |
US Patent US8476306 (2013)
BindingDB Entry DOI: 10.7270/Q2154FPH |
More data for this Ligand-Target Pair | |
Prothrombin
(Rattus norvegicus) | BDBM98587
((2R)-N-[(1S)-1-(benzyloxymethyl)-2-[(4-carbamimido...)Show SMILES NC(=N)c1ccc(CNC(=O)[C@H](COCc2ccccc2)NC(=O)[C@@H](CO)NS(=O)(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C28H33N5O6S/c29-26(30)23-13-11-20(12-14-23)15-31-27(35)25(18-39-17-21-7-3-1-4-8-21)32-28(36)24(16-34)33-40(37,38)19-22-9-5-2-6-10-22/h1-14,24-25,33-34H,15-19H2,(H3,29,30)(H,31,35)(H,32,36)/t24-,25+/m1/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| MMDB PC cid PC sid PDB UniChem
Similars
| US Patent
| 480 | -35.9 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company
US Patent
| Assay Description Inhibition constant of the compound against Thrombin |
US Patent US8476306 (2013)
BindingDB Entry DOI: 10.7270/Q2154FPH |
More data for this Ligand-Target Pair | |