Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Urokinase plasminogen activator surface receptor
(Rattus norvegicus) | BDBM98594
((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...)Show SMILES NC(=N)c1ccc(CNC(=O)CNC(=O)[C@@H](CO)NS(=O)(=O)Cc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C20H24ClN5O5S/c21-16-7-3-14(4-8-16)12-32(30,31)26-17(11-27)20(29)25-10-18(28)24-9-13-1-5-15(6-2-13)19(22)23/h1-8,17,26-27H,9-12H2,(H3,22,23)(H,24,28)(H,25,29)/t17-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| 32 | -42.6 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company
US Patent
| Assay Description Inhibition constant of the compound against Plasminogen activator urokinase |
US Patent US8476306 (2013)
BindingDB Entry DOI: 10.7270/Q2154FPH |
More data for this Ligand-Target Pair | |
Serine protease 1
(Rattus norvegicus) | BDBM98594
((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...)Show SMILES NC(=N)c1ccc(CNC(=O)CNC(=O)[C@@H](CO)NS(=O)(=O)Cc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C20H24ClN5O5S/c21-16-7-3-14(4-8-16)12-32(30,31)26-17(11-27)20(29)25-10-18(28)24-9-13-1-5-15(6-2-13)19(22)23/h1-8,17,26-27H,9-12H2,(H3,22,23)(H,24,28)(H,25,29)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| 350 | -36.7 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company
US Patent
| Assay Description Inhibition constant of the compound against Trypsin |
US Patent US8476306 (2013)
BindingDB Entry DOI: 10.7270/Q2154FPH |
More data for this Ligand-Target Pair | |
Prothrombin
(Rattus norvegicus) | BDBM98594
((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...)Show SMILES NC(=N)c1ccc(CNC(=O)CNC(=O)[C@@H](CO)NS(=O)(=O)Cc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C20H24ClN5O5S/c21-16-7-3-14(4-8-16)12-32(30,31)26-17(11-27)20(29)25-10-18(28)24-9-13-1-5-15(6-2-13)19(22)23/h1-8,17,26-27H,9-12H2,(H3,22,23)(H,24,28)(H,25,29)/t17-/m1/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| 7.90E+3 | -29.0 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company
US Patent
| Assay Description Inhibition constant of the compound against Thrombin |
US Patent US8476306 (2013)
BindingDB Entry DOI: 10.7270/Q2154FPH |
More data for this Ligand-Target Pair | |
Plasminogen
(Rattus norvegicus) | BDBM98594
((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...)Show SMILES NC(=N)c1ccc(CNC(=O)CNC(=O)[C@@H](CO)NS(=O)(=O)Cc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C20H24ClN5O5S/c21-16-7-3-14(4-8-16)12-32(30,31)26-17(11-27)20(29)25-10-18(28)24-9-13-1-5-15(6-2-13)19(22)23/h1-8,17,26-27H,9-12H2,(H3,22,23)(H,24,28)(H,25,29)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| 3.20E+4 | -25.6 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company
US Patent
| Assay Description Inhibition constant of the compound against Plasmin |
US Patent US8476306 (2013)
BindingDB Entry DOI: 10.7270/Q2154FPH |
More data for this Ligand-Target Pair | |