Found 8 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Collagenase 3
(Homo sapiens (Human)) | BDBM120184
(US8691753, 32)Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1ncccn1 |r| Show InChI InChI=1S/C23H27N5O7/c24-21(34)16(7-10-19(30)31)28-23(35)17(8-11-20(32)33)27-18(29)9-4-14-2-5-15(6-3-14)22-25-12-1-13-26-22/h1-3,5-6,12-13,16-17H,4,7-11H2,(H2,24,34)(H,27,29)(H,28,35)(H,30,31)(H,32,33)/t16-,17-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| 641 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives
US Patent
| Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... |
US Patent US8691753 (2014)
BindingDB Entry DOI: 10.7270/Q28P5Z5Q |
More data for this Ligand-Target Pair | |
Macrophage metalloelastase
(Homo sapiens (Human)) | BDBM120184
(US8691753, 32)Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1ncccn1 |r| Show InChI InChI=1S/C23H27N5O7/c24-21(34)16(7-10-19(30)31)28-23(35)17(8-11-20(32)33)27-18(29)9-4-14-2-5-15(6-3-14)22-25-12-1-13-26-22/h1-3,5-6,12-13,16-17H,4,7-11H2,(H2,24,34)(H,27,29)(H,28,35)(H,30,31)(H,32,33)/t16-,17-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| 969 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives
US Patent
| Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... |
US Patent US8691753 (2014)
BindingDB Entry DOI: 10.7270/Q28P5Z5Q |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-14 [1-20,P8S]
(Homo sapiens (Human)) | BDBM120184
(US8691753, 32)Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1ncccn1 |r| Show InChI InChI=1S/C23H27N5O7/c24-21(34)16(7-10-19(30)31)28-23(35)17(8-11-20(32)33)27-18(29)9-4-14-2-5-15(6-3-14)22-25-12-1-13-26-22/h1-3,5-6,12-13,16-17H,4,7-11H2,(H2,24,34)(H,27,29)(H,28,35)(H,30,31)(H,32,33)/t16-,17-/m0/s1 | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives
US Patent
| Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... |
US Patent US8691753 (2014)
BindingDB Entry DOI: 10.7270/Q28P5Z5Q |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM120184
(US8691753, 32)Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1ncccn1 |r| Show InChI InChI=1S/C23H27N5O7/c24-21(34)16(7-10-19(30)31)28-23(35)17(8-11-20(32)33)27-18(29)9-4-14-2-5-15(6-3-14)22-25-12-1-13-26-22/h1-3,5-6,12-13,16-17H,4,7-11H2,(H2,24,34)(H,27,29)(H,28,35)(H,30,31)(H,32,33)/t16-,17-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives
US Patent
| Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... |
US Patent US8691753 (2014)
BindingDB Entry DOI: 10.7270/Q28P5Z5Q |
More data for this Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM120184
(US8691753, 32)Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1ncccn1 |r| Show InChI InChI=1S/C23H27N5O7/c24-21(34)16(7-10-19(30)31)28-23(35)17(8-11-20(32)33)27-18(29)9-4-14-2-5-15(6-3-14)22-25-12-1-13-26-22/h1-3,5-6,12-13,16-17H,4,7-11H2,(H2,24,34)(H,27,29)(H,28,35)(H,30,31)(H,32,33)/t16-,17-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives
US Patent
| Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... |
US Patent US8691753 (2014)
BindingDB Entry DOI: 10.7270/Q28P5Z5Q |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM120184
(US8691753, 32)Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1ncccn1 |r| Show InChI InChI=1S/C23H27N5O7/c24-21(34)16(7-10-19(30)31)28-23(35)17(8-11-20(32)33)27-18(29)9-4-14-2-5-15(6-3-14)22-25-12-1-13-26-22/h1-3,5-6,12-13,16-17H,4,7-11H2,(H2,24,34)(H,27,29)(H,28,35)(H,30,31)(H,32,33)/t16-,17-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives
US Patent
| Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... |
US Patent US8691753 (2014)
BindingDB Entry DOI: 10.7270/Q28P5Z5Q |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM120184
(US8691753, 32)Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1ncccn1 |r| Show InChI InChI=1S/C23H27N5O7/c24-21(34)16(7-10-19(30)31)28-23(35)17(8-11-20(32)33)27-18(29)9-4-14-2-5-15(6-3-14)22-25-12-1-13-26-22/h1-3,5-6,12-13,16-17H,4,7-11H2,(H2,24,34)(H,27,29)(H,28,35)(H,30,31)(H,32,33)/t16-,17-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives
US Patent
| Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... |
US Patent US8691753 (2014)
BindingDB Entry DOI: 10.7270/Q28P5Z5Q |
More data for this Ligand-Target Pair | |
Stromelysin-2
(Homo sapiens (Human)) | BDBM120184
(US8691753, 32)Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1ncccn1 |r| Show InChI InChI=1S/C23H27N5O7/c24-21(34)16(7-10-19(30)31)28-23(35)17(8-11-20(32)33)27-18(29)9-4-14-2-5-15(6-3-14)22-25-12-1-13-26-22/h1-3,5-6,12-13,16-17H,4,7-11H2,(H2,24,34)(H,27,29)(H,28,35)(H,30,31)(H,32,33)/t16-,17-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives
US Patent
| Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... |
US Patent US8691753 (2014)
BindingDB Entry DOI: 10.7270/Q28P5Z5Q |
More data for this Ligand-Target Pair | |