Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 339.4 BDBM50121006

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50121006 (4-[2-(4-Benzyl-phenoxy)-ethyl]-piperazine-1-carbox...) Show SMILES NC(=O)N1CCN(CCOc2ccc(Cc3ccccc3)cc2)CC1 Show InChI InChI=1S/C20H25N3O2/c21-20(24)23-12-10-22(11-13-23)14-15-25-19-8-6-18(7-9-19)16-17-4-2-1-3-5-17/h1-9H,10-16H2,(H2,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation Curated by ChEMBL					Assay Description Inhibition of leukotriene A4 hydrolase in human recombinant assay				Bioorg Med Chem Lett 12: 3383-6 (2002) BindingDB Entry DOI: 10.7270/Q2N8795W
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