Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 311.3 BDBM121419

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM121419 (US8722709, 22) Show SMILES NC(=O)Nc1cc(ccn1)-c1ccnn1Cc1ccc(F)cc1 Show InChI InChI=1S/C16H14FN5O/c17-13-3-1-11(2-4-13)10-22-14(6-8-20-22)12-5-7-19-15(9-12)21-16(18)23/h1-9H,10H2,(H3,18,19,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The MR competitive binding assay is based on the binding and displacement of a TAMRA-labeled Dexamethasone probe with fluorescence polarization (FP) ...				US Patent US8722709 (2014) BindingDB Entry DOI: 10.7270/Q2NS0SJ4
					More data for this Ligand-Target Pair