Found 12 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Casein kinase 1, delta tv1
(Sus scrofa) | BDBM50274742
(CHEMBL4129279)Show SMILES NC(=O)c1c(O)cc(O)c2c1oc1c2[nH]c(=O)[nH]c1=O Show InChI InChI=1S/C11H7N3O6/c12-9(17)5-3(16)1-2(15)4-6-8(20-7(4)5)10(18)14-11(19)13-6/h1,15-16H,(H2,12,17)(H2,13,14,18,19) | PDB
UniProtKB/TrEMBL
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description
Tested for thromboxane antagonist potency (pA2) against U 44619 induced platelet aggregation using human platelet rich plasma |
Bioorg Med Chem Lett 28: 2250-2255 (2018)
Article DOI: 10.1016/j.bmcl.2018.05.044
BindingDB Entry DOI: 10.7270/Q2G44SSP |
More data for this
Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50274742
(CHEMBL4129279)Show SMILES NC(=O)c1c(O)cc(O)c2c1oc1c2[nH]c(=O)[nH]c1=O Show InChI InChI=1S/C11H7N3O6/c12-9(17)5-3(16)1-2(15)4-6-8(20-7(4)5)10(18)14-11(19)13-6/h1,15-16H,(H2,12,17)(H2,13,14,18,19) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description
Inhibition of human Aurora-B using full-length histone H3 as substrate after 10 mins |
Bioorg Med Chem Lett 28: 2250-2255 (2018)
Article DOI: 10.1016/j.bmcl.2018.05.044
BindingDB Entry DOI: 10.7270/Q2G44SSP |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase haspin
(Homo sapiens (Human)) | BDBM50274742
(CHEMBL4129279)Show SMILES NC(=O)c1c(O)cc(O)c2c1oc1c2[nH]c(=O)[nH]c1=O Show InChI InChI=1S/C11H7N3O6/c12-9(17)5-3(16)1-2(15)4-6-8(20-7(4)5)10(18)14-11(19)13-6/h1,15-16H,(H2,12,17)(H2,13,14,18,19) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description
Inhibition of human haspin using full-length histone H3 as substrate after 10 mins |
Bioorg Med Chem Lett 28: 2250-2255 (2018)
Article DOI: 10.1016/j.bmcl.2018.05.044
BindingDB Entry DOI: 10.7270/Q2G44SSP |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50274742
(CHEMBL4129279)Show SMILES NC(=O)c1c(O)cc(O)c2c1oc1c2[nH]c(=O)[nH]c1=O Show InChI InChI=1S/C11H7N3O6/c12-9(17)5-3(16)1-2(15)4-6-8(20-7(4)5)10(18)14-11(19)13-6/h1,15-16H,(H2,12,17)(H2,13,14,18,19) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description
Inhibition of mouse CLK1 using Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 30 mins by LANCE assay |
Bioorg Med Chem Lett 28: 2250-2255 (2018)
Article DOI: 10.1016/j.bmcl.2018.05.044
BindingDB Entry DOI: 10.7270/Q2G44SSP |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform epsilon
(Sus scrofa) | BDBM50274742
(CHEMBL4129279)Show SMILES NC(=O)c1c(O)cc(O)c2c1oc1c2[nH]c(=O)[nH]c1=O Show InChI InChI=1S/C11H7N3O6/c12-9(17)5-3(16)1-2(15)4-6-8(20-7(4)5)10(18)14-11(19)13-6/h1,15-16H,(H2,12,17)(H2,13,14,18,19) | PDB
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description
Inhibition of pig CK1epsilon using Ulight-ARTKQTARKSTGGKAPRKQLAGCG as substrate after 60 mins by LANCE assay |
Bioorg Med Chem Lett 28: 2250-2255 (2018)
Article DOI: 10.1016/j.bmcl.2018.05.044
BindingDB Entry DOI: 10.7270/Q2G44SSP |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Sus scrofa) | BDBM50274742
(CHEMBL4129279)Show SMILES NC(=O)c1c(O)cc(O)c2c1oc1c2[nH]c(=O)[nH]c1=O Show InChI InChI=1S/C11H7N3O6/c12-9(17)5-3(16)1-2(15)4-6-8(20-7(4)5)10(18)14-11(19)13-6/h1,15-16H,(H2,12,17)(H2,13,14,18,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description
Inhibition of pig GSK3beta using Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 90 mins by LANCE assay |
Bioorg Med Chem Lett 28: 2250-2255 (2018)
Article DOI: 10.1016/j.bmcl.2018.05.044
BindingDB Entry DOI: 10.7270/Q2G44SSP |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50274742
(CHEMBL4129279)Show SMILES NC(=O)c1c(O)cc(O)c2c1oc1c2[nH]c(=O)[nH]c1=O Show InChI InChI=1S/C11H7N3O6/c12-9(17)5-3(16)1-2(15)4-6-8(20-7(4)5)10(18)14-11(19)13-6/h1,15-16H,(H2,12,17)(H2,13,14,18,19) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description
Inhibition of human CDK5/p25 |
Bioorg Med Chem Lett 28: 2250-2255 (2018)
Article DOI: 10.1016/j.bmcl.2018.05.044
BindingDB Entry DOI: 10.7270/Q2G44SSP |
More data for this
Ligand-Target Pair | |
Cyclin-T1/Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM50274742
(CHEMBL4129279)Show SMILES NC(=O)c1c(O)cc(O)c2c1oc1c2[nH]c(=O)[nH]c1=O Show InChI InChI=1S/C11H7N3O6/c12-9(17)5-3(16)1-2(15)4-6-8(20-7(4)5)10(18)14-11(19)13-6/h1,15-16H,(H2,12,17)(H2,13,14,18,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human CDK9/CyclinT using Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 90 mins by LANCE assay |
Bioorg Med Chem Lett 28: 2250-2255 (2018)
Article DOI: 10.1016/j.bmcl.2018.05.044
BindingDB Entry DOI: 10.7270/Q2G44SSP |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50274742
(CHEMBL4129279)Show SMILES NC(=O)c1c(O)cc(O)c2c1oc1c2[nH]c(=O)[nH]c1=O Show InChI InChI=1S/C11H7N3O6/c12-9(17)5-3(16)1-2(15)4-6-8(20-7(4)5)10(18)14-11(19)13-6/h1,15-16H,(H2,12,17)(H2,13,14,18,19) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human PIM1 using CREBtide as substrate after 60 mins by LANCE assay |
Bioorg Med Chem Lett 28: 2250-2255 (2018)
Article DOI: 10.1016/j.bmcl.2018.05.044
BindingDB Entry DOI: 10.7270/Q2G44SSP |
More data for this
Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50274742
(CHEMBL4129279)Show SMILES NC(=O)c1c(O)cc(O)c2c1oc1c2[nH]c(=O)[nH]c1=O Show InChI InChI=1S/C11H7N3O6/c12-9(17)5-3(16)1-2(15)4-6-8(20-7(4)5)10(18)14-11(19)13-6/h1,15-16H,(H2,12,17)(H2,13,14,18,19) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description
Inhibition of rat Dyrk1a using Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 30 mins by LANCE assay |
Bioorg Med Chem Lett 28: 2250-2255 (2018)
Article DOI: 10.1016/j.bmcl.2018.05.044
BindingDB Entry DOI: 10.7270/Q2G44SSP |
More data for this
Ligand-Target Pair | |
[Tau protein] kinase
(Sus scrofa) | BDBM50274742
(CHEMBL4129279)Show SMILES NC(=O)c1c(O)cc(O)c2c1oc1c2[nH]c(=O)[nH]c1=O Show InChI InChI=1S/C11H7N3O6/c12-9(17)5-3(16)1-2(15)4-6-8(20-7(4)5)10(18)14-11(19)13-6/h1,15-16H,(H2,12,17)(H2,13,14,18,19) | PDB
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description
Inhibition of pig GSK3alpha using Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 60 mins by LANCE assay |
Bioorg Med Chem Lett 28: 2250-2255 (2018)
Article DOI: 10.1016/j.bmcl.2018.05.044
BindingDB Entry DOI: 10.7270/Q2G44SSP |
More data for this
Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50274742
(CHEMBL4129279)Show SMILES NC(=O)c1c(O)cc(O)c2c1oc1c2[nH]c(=O)[nH]c1=O Show InChI InChI=1S/C11H7N3O6/c12-9(17)5-3(16)1-2(15)4-6-8(20-7(4)5)10(18)14-11(19)13-6/h1,15-16H,(H2,12,17)(H2,13,14,18,19) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human CDK2/Cyclin A using ATP and Ulight-CFFKNIVTPRTPPPSQGK-amide as substrate after 30 mins by LANCE assay |
Bioorg Med Chem Lett 28: 2250-2255 (2018)
Article DOI: 10.1016/j.bmcl.2018.05.044
BindingDB Entry DOI: 10.7270/Q2G44SSP |
More data for this
Ligand-Target Pair | |