Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 454.9 BDBM207017

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM207017 (US9233965, 102) Show SMILES NC(=O)c1c2CN(CCn2c(Cl)c1-c1cccc(F)c1)C(=O)NC1CCS(=O)(=O)C1 Show InChI InChI=1S/C19H20ClFN4O4S/c20-17-15(11-2-1-3-12(21)8-11)16(18(22)26)14-9-24(5-6-25(14)17)19(27)23-13-4-7-30(28,29)10-13/h1-3,8,13H,4-7,9-10H2,(H2,22,26)(H,23,27)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.5	25
SANOFI US Patent					Assay Description "U"-bottomed Falcon plates are prepared by placing 5 uL of solutions of the compounds according to the invention at concentrations of 10, 1, 0.1, 0.0...				US Patent US9233965 (2016) BindingDB Entry DOI: 10.7270/Q2086443
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