Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 446.8 BDBM206914

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM206914 (US9233965, 81) Show SMILES NC(=O)c1c2CN(CCn2c(Cl)c1-c1cccc(F)c1)C(=O)NCCCC(F)(F)F Show InChI InChI=1S/C19H19ClF4N4O2/c20-16-14(11-3-1-4-12(21)9-11)15(17(25)29)13-10-27(7-8-28(13)16)18(30)26-6-2-5-19(22,23)24/h1,3-4,9H,2,5-8,10H2,(H2,25,29)(H,26,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	7.5	25
SANOFI US Patent					Assay Description "U"-bottomed Falcon plates are prepared by placing 5 uL of solutions of the compounds according to the invention at concentrations of 10, 1, 0.1, 0.0...				US Patent US9233965 (2016) BindingDB Entry DOI: 10.7270/Q2086443
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