Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM302637
(2-(3-Chloro-4- fluorophenyl)-N5-(4- cyano-3-(trifl...)Show SMILES NC(=O)c1c2CN(CCn2nc1-c1ccc(F)c(Cl)c1)C(=O)Nc1ccc([N+]#[C-])c(c1)C(F)(F)F |$;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;;$| Show InChI InChI=1S/C22H15ClF4N6O2/c1-29-16-5-3-12(9-13(16)22(25,26)27)30-21(35)32-6-7-33-17(10-32)18(20(28)34)19(31-33)11-2-4-15(24)14(23)8-11/h2-5,8-9H,6-7,10H2,(H2,28,34)(H,30,35) | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst... |
US Patent US9598423 (2017)
BindingDB Entry DOI: 10.7270/Q2FJ2JT9 |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform epsilon
(Homo sapiens (Human)) | BDBM302637
(2-(3-Chloro-4- fluorophenyl)-N5-(4- cyano-3-(trifl...)Show SMILES NC(=O)c1c2CN(CCn2nc1-c1ccc(F)c(Cl)c1)C(=O)Nc1ccc([N+]#[C-])c(c1)C(F)(F)F |$;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;;$| Show InChI InChI=1S/C22H15ClF4N6O2/c1-29-16-5-3-12(9-13(16)22(25,26)27)30-21(35)32-6-7-33-17(10-32)18(20(28)34)19(31-33)11-2-4-15(24)14(23)8-11/h2-5,8-9H,6-7,10H2,(H2,28,34)(H,30,35) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst... |
US Patent US9598423 (2017)
BindingDB Entry DOI: 10.7270/Q2FJ2JT9 |
More data for this
Ligand-Target Pair | |