Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM302446
(N5-(4,4- Difluorocyclohexyl)-2- (3-fluorophenyl)-6...)Show SMILES NC(=O)c1c2CN(CCn2nc1-c1cccc(F)c1)C(=O)NC1CCC(F)(F)CC1 Show InChI InChI=1S/C20H22F3N5O2/c21-13-3-1-2-12(10-13)17-16(18(24)29)15-11-27(8-9-28(15)26-17)19(30)25-14-4-6-20(22,23)7-5-14/h1-3,10,14H,4-9,11H2,(H2,24,29)(H,25,30) | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst... |
US Patent US9598423 (2017)
BindingDB Entry DOI: 10.7270/Q2FJ2JT9 |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform epsilon
(Homo sapiens (Human)) | BDBM302446
(N5-(4,4- Difluorocyclohexyl)-2- (3-fluorophenyl)-6...)Show SMILES NC(=O)c1c2CN(CCn2nc1-c1cccc(F)c1)C(=O)NC1CCC(F)(F)CC1 Show InChI InChI=1S/C20H22F3N5O2/c21-13-3-1-2-12(10-13)17-16(18(24)29)15-11-27(8-9-28(15)26-17)19(30)25-14-4-6-20(22,23)7-5-14/h1-3,10,14H,4-9,11H2,(H2,24,29)(H,25,30) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst... |
US Patent US9598423 (2017)
BindingDB Entry DOI: 10.7270/Q2FJ2JT9 |
More data for this
Ligand-Target Pair | |