Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 275.7 BDBM50164742

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50164742 (CHEMBL3800219) Show SMILES NC(=O)c1cc(Cl)cn(CCc2ccccc2)c1=N Show InChI InChI=1S/C14H14ClN3O/c15-11-8-12(14(17)19)13(16)18(9-11)7-6-10-4-2-1-3-5-10/h1-5,8-9,16H,6-7H2,(H2,17,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Displacement of 7-methoxy-[3H]-prazosin from human alpha1D adrenergic receptor expressed in CHO-K1 cell membranes incubated for 60 mins by liquid sci...				J Med Chem 59: 2989-3002 (2016) Article DOI: 10.1021/acs.jmedchem.5b01528 BindingDB Entry DOI: 10.7270/Q20G3N2B
					More data for this Ligand-Target Pair