Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Mitogen-activated protein kinase kinase kinase 11
(Homo sapiens (Human)) | BDBM354872
(Preparation of 4-{5-[4-(piperazine-1-carbonyl)-phe...)Show SMILES NC(=O)c1ccc(cc1)-c1c[nH]c2ncc(cc12)-c1ccc(cc1)C(=O)N1CC[NH2+]CC1 Show InChI InChI=1S/C25H23N5O2/c26-23(31)18-5-3-17(4-6-18)22-15-29-24-21(22)13-20(14-28-24)16-1-7-19(8-2-16)25(32)30-11-9-27-10-12-30/h1-8,13-15,27H,9-12H2,(H2,26,31)(H,28,29)/p+1 | PDB
NCI pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Rochester; Board of Regents of the University of Nebraska
US Patent
| Assay Description
200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ... |
US Patent US10485800 (2019)
BindingDB Entry DOI: 10.7270/Q22B91DW |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase 11
(Homo sapiens (Human)) | BDBM354872
(Preparation of 4-{5-[4-(piperazine-1-carbonyl)-phe...)Show SMILES NC(=O)c1ccc(cc1)-c1c[nH]c2ncc(cc12)-c1ccc(cc1)C(=O)N1CC[NH2+]CC1 Show InChI InChI=1S/C25H23N5O2/c26-23(31)18-5-3-17(4-6-18)22-15-29-24-21(22)13-20(14-28-24)16-1-7-19(8-2-16)25(32)30-11-9-27-10-12-30/h1-8,13-15,27H,9-12H2,(H2,26,31)(H,28,29)/p+1 | PDB
NCI pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Rochester
US Patent
| Assay Description
200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ... |
US Patent US9814704 (2017)
BindingDB Entry DOI: 10.7270/Q27H1MRN |
More data for this
Ligand-Target Pair | |