Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM202516
(US9238658, 39)Show SMILES NC(=O)c1cccc(NC(=O)N2CCC(CC2)n2ncc3c(F)cccc23)c1 Show InChI InChI=1S/C20H20FN5O2/c21-17-5-2-6-18-16(17)12-23-26(18)15-7-9-25(10-8-15)20(28)24-14-4-1-3-13(11-14)19(22)27/h1-6,11-12,15H,7-10H2,(H2,22,27)(H,24,28) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | 25 |
Janssen Pharmaceutica NV
US Patent
| Assay Description
The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac... |
US Patent US9238658 (2016)
BindingDB Entry DOI: 10.7270/Q2930S1D |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM202516
(US9238658, 39)Show SMILES NC(=O)c1cccc(NC(=O)N2CCC(CC2)n2ncc3c(F)cccc23)c1 Show InChI InChI=1S/C20H20FN5O2/c21-17-5-2-6-18-16(17)12-23-26(18)15-7-9-25(10-8-15)20(28)24-14-4-1-3-13(11-14)19(22)27/h1-6,11-12,15H,7-10H2,(H2,22,27)(H,24,28) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 88 | n/a | n/a | n/a | n/a | n/a | 25 |
Janssen Pharmaceutica NV
US Patent
| Assay Description
The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac... |
US Patent US9238658 (2016)
BindingDB Entry DOI: 10.7270/Q2930S1D |
More data for this
Ligand-Target Pair | |