Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Metabotropic glutamate receptor 1
(RAT) | BDBM50208760
((RS)-2-amino-(5-bromo-1-hydroxy-4-pyrazolyl) aceti...)Show InChI InChI=1S/C5H6BrN3O3/c6-4-2(1-8-9(4)12)3(7)5(10)11/h1,3,12H,7H2,(H,10,11) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description Agonist activity at rat mGluR1a receptor expressed in CHO cells assessed as effect on intracellular calcium level |
Bioorg Med Chem 15: 3524-38 (2007)
Article DOI: 10.1016/j.bmc.2007.02.047 BindingDB Entry DOI: 10.7270/Q2XD11CV |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50208760
((RS)-2-amino-(5-bromo-1-hydroxy-4-pyrazolyl) aceti...)Show InChI InChI=1S/C5H6BrN3O3/c6-4-2(1-8-9(4)12)3(7)5(10)11/h1,3,12H,7H2,(H,10,11) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 1.70E+5 | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description Agonist activity at rat mGluR2 receptor expressed in CHO cells assessed as effect on intracellular cAMP level |
Bioorg Med Chem 15: 3524-38 (2007)
Article DOI: 10.1016/j.bmc.2007.02.047 BindingDB Entry DOI: 10.7270/Q2XD11CV |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Rattus norvegicus (Rat)) | BDBM50208760
((RS)-2-amino-(5-bromo-1-hydroxy-4-pyrazolyl) aceti...)Show InChI InChI=1S/C5H6BrN3O3/c6-4-2(1-8-9(4)12)3(7)5(10)11/h1,3,12H,7H2,(H,10,11) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description Agonist activity at rat mGluR4 receptor expressed in CHO cells assessed as effect on intracellular cAMP level |
Bioorg Med Chem 15: 3524-38 (2007)
Article DOI: 10.1016/j.bmc.2007.02.047 BindingDB Entry DOI: 10.7270/Q2XD11CV |
More data for this Ligand-Target Pair | |