Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 247.2 BDBM50208765

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50208765 ((RS)-2-amino-(5-benzyl-1-hydroxy-4-pyrazolyl)aceti...) Show SMILES NC(C(O)=O)c1cnn(O)c1Cc1ccccc1 |w:1.0| Show InChI InChI=1S/C12H13N3O3/c13-11(12(16)17)9-7-14-15(18)10(9)6-8-4-2-1-3-5-8/h1-5,7,11,18H,6,13H2,(H,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR2 receptor expressed in CHO cells assessed as effect on intracellular cAMP level				Bioorg Med Chem 15: 3524-38 (2007) Article DOI: 10.1016/j.bmc.2007.02.047 BindingDB Entry DOI: 10.7270/Q2XD11CV
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50208765 ((RS)-2-amino-(5-benzyl-1-hydroxy-4-pyrazolyl)aceti...) Show SMILES NC(C(O)=O)c1cnn(O)c1Cc1ccccc1 |w:1.0| Show InChI InChI=1S/C12H13N3O3/c13-11(12(16)17)9-7-14-15(18)10(9)6-8-4-2-1-3-5-8/h1-5,7,11,18H,6,13H2,(H,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Agonist activity at rat mGluR1a receptor expressed in CHO cells assessed as effect on intracellular calcium level				Bioorg Med Chem 15: 3524-38 (2007) Article DOI: 10.1016/j.bmc.2007.02.047 BindingDB Entry DOI: 10.7270/Q2XD11CV
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50208765 ((RS)-2-amino-(5-benzyl-1-hydroxy-4-pyrazolyl)aceti...) Show SMILES NC(C(O)=O)c1cnn(O)c1Cc1ccccc1 |w:1.0| Show InChI InChI=1S/C12H13N3O3/c13-11(12(16)17)9-7-14-15(18)10(9)6-8-4-2-1-3-5-8/h1-5,7,11,18H,6,13H2,(H,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Agonist activity at rat mGluR4 receptor expressed in CHO cells assessed as effect on intracellular cAMP level				Bioorg Med Chem 15: 3524-38 (2007) Article DOI: 10.1016/j.bmc.2007.02.047 BindingDB Entry DOI: 10.7270/Q2XD11CV
					More data for this Ligand-Target Pair