Found 5 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50170882
(CHEMBL3804856)Show InChI InChI=1S/C18H29N2O4P/c19-17(12-20-16-9-5-2-6-10-16)25(23,24)13-15(18(21)22)11-14-7-3-1-4-8-14/h1,3-4,7-8,15-17,20H,2,5-6,9-13,19H2,(H,21,22)(H,23,24) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 275 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea... |
Eur J Med Chem 117: 187-96 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.018 BindingDB Entry DOI: 10.7270/Q2BC41F8 |
More data for this Ligand-Target Pair | |
Aminopeptidase N
(Sus scrofa (Pig)) | BDBM50170882
(CHEMBL3804856)Show InChI InChI=1S/C18H29N2O4P/c19-17(12-20-16-9-5-2-6-10-16)25(23,24)13-15(18(21)22)11-14-7-3-1-4-8-14/h1,3-4,7-8,15-17,20H,2,5-6,9-13,19H2,(H,21,22)(H,23,24) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 3.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology
Curated by ChEMBL
| Assay Description Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f... |
Eur J Med Chem 117: 187-96 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.018 BindingDB Entry DOI: 10.7270/Q2BC41F8 |
More data for this Ligand-Target Pair | |
Endoplasmic reticulum aminopeptidase 2
(Homo sapiens (Human)) | BDBM50170882
(CHEMBL3804856)Show InChI InChI=1S/C18H29N2O4P/c19-17(12-20-16-9-5-2-6-10-16)25(23,24)13-15(18(21)22)11-14-7-3-1-4-8-14/h1,3-4,7-8,15-17,20H,2,5-6,9-13,19H2,(H,21,22)(H,23,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 7.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology
Curated by ChEMBL
| Assay Description Inhibition of human ERAP2 preincubated for 30 to 60 mins followed by addition of Arg-AMC as substrate measured for 15 mins by spectrofluorimetric met... |
Bioorg Med Chem Lett 26: 4122-6 (2016)
Article DOI: 10.1016/j.bmcl.2016.06.062 BindingDB Entry DOI: 10.7270/Q2TT4SW1 |
More data for this Ligand-Target Pair | |
Cytosol aminopeptidase [33-68,L62W]
(Sus scrofa (Pig)) | BDBM50170882
(CHEMBL3804856)Show InChI InChI=1S/C18H29N2O4P/c19-17(12-20-16-9-5-2-6-10-16)25(23,24)13-15(18(21)22)11-14-7-3-1-4-8-14/h1,3-4,7-8,15-17,20H,2,5-6,9-13,19H2,(H,21,22)(H,23,24) | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 2.83E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology
Curated by ChEMBL
| Assay Description Inhibition of porcine kidney leucine aminopeptidase M17 using Leu-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition meas... |
Eur J Med Chem 117: 187-96 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.018 BindingDB Entry DOI: 10.7270/Q2BC41F8 |
More data for this Ligand-Target Pair | |
Endoplasmic reticulum aminopeptidase 1
(Homo sapiens (Human)) | BDBM50170882
(CHEMBL3804856)Show InChI InChI=1S/C18H29N2O4P/c19-17(12-20-16-9-5-2-6-10-16)25(23,24)13-15(18(21)22)11-14-7-3-1-4-8-14/h1,3-4,7-8,15-17,20H,2,5-6,9-13,19H2,(H,21,22)(H,23,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| >2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology
Curated by ChEMBL
| Assay Description Inhibition of human ERAP1 preincubated for 30 to 60 mins followed by addition of Leu-AMC as substrate measured for 15 mins by spectrofluorimetric met... |
Bioorg Med Chem Lett 26: 4122-6 (2016)
Article DOI: 10.1016/j.bmcl.2016.06.062 BindingDB Entry DOI: 10.7270/Q2TT4SW1 |
More data for this Ligand-Target Pair | |