Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Amiloride-sensitive sodium channel subunit alpha
(Homo sapiens (Human)) | BDBM115076
(3,5-bis(azanyl)-N-[azanyl(phenylazanyl)methylidene...)Show SMILES NC(NC(=O)c1nc(Cl)c(N)nc1N)=Nc1ccccc1 |w:14.15| Show InChI InChI=1S/C12H12ClN7O/c13-8-10(15)19-9(14)7(18-8)11(21)20-12(16)17-6-4-2-1-3-5-6/h1-5H,(H4,14,15,19)(H3,16,17,20,21) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 401 | n/a | n/a | n/a | n/a | n/a | n/a |
Parion Sciences Inc.
Curated by ChEMBL
| Assay Description Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assay |
J Med Chem 49: 4098-115 (2006)
Article DOI: 10.1021/jm051134w BindingDB Entry DOI: 10.7270/Q2FT8KNH |
More data for this Ligand-Target Pair | |
Oxysterols receptor LXR-beta
(Homo sapiens (Human)) | BDBM115076
(3,5-bis(azanyl)-N-[azanyl(phenylazanyl)methylidene...)Show SMILES NC(NC(=O)c1nc(Cl)c(N)nc1N)=Nc1ccccc1 |w:14.15| Show InChI InChI=1S/C12H12ClN7O/c13-8-10(15)19-9(14)7(18-8)11(21)20-12(16)17-6-4-2-1-3-5-6/h1-5H,(H4,14,15,19)(H3,16,17,20,21) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | n/a | n/a | 6.75E+4 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,... |
PubChem Bioassay (2013)
BindingDB Entry DOI: 10.7270/Q2ZP44SP |
More data for this Ligand-Target Pair | |