Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Aminopeptidase N
(Homo sapiens (Human)) | BDBM50336494
(6-amino-5,6,8,9-tetrahydrobenzocycloheptene-7-one,...)Show InChI InChI=1S/C11H13NO/c12-10-7-9-4-2-1-3-8(9)5-6-11(10)13/h1-4,10H,5-7,12H2 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire de Chimie Organique et Bioorganique, FRE3252, ENSCMu, F-68093 Mulhouse Cedex, France.
Curated by ChEMBL
| Assay Description Inhibition of human aminopeptidase N by Dixon plot analysis |
Bioorg Med Chem 19: 1434-49 (2011)
Article DOI: 10.1016/j.bmc.2011.01.008 BindingDB Entry DOI: 10.7270/Q2G44QJQ |
More data for this Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50336494
(6-amino-5,6,8,9-tetrahydrobenzocycloheptene-7-one,...)Show InChI InChI=1S/C11H13NO/c12-10-7-9-4-2-1-3-8(9)5-6-11(10)13/h1-4,10H,5-7,12H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire de Chimie Organique et Bioorganique, FRE3252, ENSCMu, F-68093 Mulhouse Cedex, France.
Curated by ChEMBL
| Assay Description Inhibition of aminopeptidase activity of human leukotriene A4 hydrolase by Dixon plot analysis |
Bioorg Med Chem 19: 1434-49 (2011)
Article DOI: 10.1016/j.bmc.2011.01.008 BindingDB Entry DOI: 10.7270/Q2G44QJQ |
More data for this Ligand-Target Pair | |
Cytosol aminopeptidase
(Bos taurus (bovine)) | BDBM50336494
(6-amino-5,6,8,9-tetrahydrobenzocycloheptene-7-one,...)Show InChI InChI=1S/C11H13NO/c12-10-7-9-4-2-1-3-8(9)5-6-11(10)13/h1-4,10H,5-7,12H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire de Chimie Organique et Bioorganique, FRE3252, ENSCMu, F-68093 Mulhouse Cedex, France.
Curated by ChEMBL
| Assay Description Inhibition of bovine lens cytosolic leucine aminopeptidase by Dixon plot analysis |
Bioorg Med Chem 19: 1434-49 (2011)
Article DOI: 10.1016/j.bmc.2011.01.008 BindingDB Entry DOI: 10.7270/Q2G44QJQ |
More data for this Ligand-Target Pair | |