Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Proline-rich AKT1 substrate 1
(Homo sapiens (Human)) | BDBM386010
(2-[4-(5,6,7,8-Tetrahydro-pyrido[2,3-d]pyrimidin-4-...)Show SMILES NCC(N1CCN(CC1)c1ncnc2NCCCc12)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C20H25F3N6/c21-20(22,23)15-5-3-14(4-6-15)17(12-24)28-8-10-29(11-9-28)19-16-2-1-7-25-18(16)26-13-27-19/h3-6,13,17H,1-2,7-12,24H2,(H,25,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin at Madison
| Assay Description
A TTP Mosquito liquid handling instrument was used to place 125 nl of the appropriate concentration of inhibitor in 100% DMSO (for a dose response cu... |
J Med Chem 51: 7243-52 (2008)
BindingDB Entry DOI: 10.7270/Q26M394B |
More data for this
Ligand-Target Pair | |
Ribosomal protein S6 kinase beta-1 [T412E]
(Homo sapiens (Human)) | BDBM386010
(2-[4-(5,6,7,8-Tetrahydro-pyrido[2,3-d]pyrimidin-4-...)Show SMILES NCC(N1CCN(CC1)c1ncnc2NCCCc12)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C20H25F3N6/c21-20(22,23)15-5-3-14(4-6-15)17(12-24)28-8-10-29(11-9-28)19-16-2-1-7-25-18(16)26-13-27-19/h3-6,13,17H,1-2,7-12,24H2,(H,25,26,27) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wisconsin at Madison
| Assay Description
P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com... |
J Med Chem 51: 7243-52 (2008)
BindingDB Entry DOI: 10.7270/Q26M394B |
More data for this
Ligand-Target Pair | |