Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 438.5 BDBM50514085

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen (Homo sapiens (Human))	BDBM50514085 (CHEMBL4456758) Show SMILES NCCCCCC(=O)N[C@@H](CCCCN)C(=O)Nc1ccc(cc1)C(=O)c1ccccc1 |r| Show InChI InChI=1S/C25H34N4O3/c26-17-7-2-5-12-23(30)29-22(11-6-8-18-27)25(32)28-21-15-13-20(14-16-21)24(31)19-9-3-1-4-10-19/h1,3-4,9-10,13-16,22H,2,5-8,11-12,17-18,26-27H2,(H,28,32)(H,29,30)/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Philipps University Marburg Curated by ChEMBL					Assay Description Inhibition of plasmin (unknown origin) assessed as reduction in amidolytic activity using S-2251 as the substrate after 4 mins				J Med Chem 63: 1445-1472 (2020) Article DOI: 10.1021/acs.jmedchem.9b01060 BindingDB Entry DOI: 10.7270/Q2VQ361P
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