Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 229.2 BDBM50246062Purchase

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50246062 (2-(4-phenoxyphenoxy)ethanamine | CHEMBL472386) Show SMILES NCCOc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C14H15NO2/c15-10-11-16-12-6-8-14(9-7-12)17-13-4-2-1-3-5-13/h1-9H,10-11,15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of epoxide hydrolase activity of human leukotriene A4 hydrolase assessed as LTB4 level by ELISA				J Med Chem 51: 7882-8 (2008) Article DOI: 10.1021/jm8010096 BindingDB Entry DOI: 10.7270/Q2VH5NQQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50246062 (2-(4-phenoxyphenoxy)ethanamine | CHEMBL472386) Show SMILES NCCOc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C14H15NO2/c15-10-11-16-12-6-8-14(9-7-12)17-13-4-2-1-3-5-13/h1-9H,10-11,15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of epoxide hydrolase activity of human recombinant leukotriene A4 hydrolase expressed in Escherichia coli assessed as LTB4 production by R...				Bioorg Med Chem Lett 18: 6549-52 (2008) Article DOI: 10.1016/j.bmcl.2008.10.044 BindingDB Entry DOI: 10.7270/Q2KS6RDK
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50246062 (2-(4-phenoxyphenoxy)ethanamine | CHEMBL472386) Show SMILES NCCOc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C14H15NO2/c15-10-11-16-12-6-8-14(9-7-12)17-13-4-2-1-3-5-13/h1-9H,10-11,15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	228	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of aminopeptidase activity of human recombinant leukotriene A4 hydrolase expressed in Escherichia coli assessed as p-nitroanilide release ...				Bioorg Med Chem Lett 18: 6549-52 (2008) Article DOI: 10.1016/j.bmcl.2008.10.044 BindingDB Entry DOI: 10.7270/Q2KS6RDK
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50246062 (2-(4-phenoxyphenoxy)ethanamine | CHEMBL472386) Show SMILES NCCOc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C14H15NO2/c15-10-11-16-12-6-8-14(9-7-12)17-13-4-2-1-3-5-13/h1-9H,10-11,15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	228	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of aminopeptidase activity of human leukotriene A4 hydrolase assessed as para-nitroanilide release by spectrophotometry				J Med Chem 51: 7882-8 (2008) Article DOI: 10.1021/jm8010096 BindingDB Entry DOI: 10.7270/Q2VH5NQQ
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50246062 (2-(4-phenoxyphenoxy)ethanamine | CHEMBL472386) Show SMILES NCCOc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C14H15NO2/c15-10-11-16-12-6-8-14(9-7-12)17-13-4-2-1-3-5-13/h1-9H,10-11,15H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of human nonpancreatic secretory phospholipase A2				J Med Chem 51: 7882-8 (2008) Article DOI: 10.1021/jm8010096 BindingDB Entry DOI: 10.7270/Q2VH5NQQ
					More data for this Ligand-Target Pair