Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 443.5 BDBM50574026

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NEDD8-activating enzyme E1 regulatory subunit (Homo sapiens (Human))	BDBM50574026 (CHEMBL4282603) Show SMILES NS(=O)(=O)OC[C@@H]1C[C@H](C[C@@H]1O)n1ccc2c(N[C@@H]3CCc4ccccc34)ncnc12 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NAE1 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113801 BindingDB Entry DOI: 10.7270/Q2280CFC
					More data for this Ligand-Target Pair