Found 7 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Gag-Pol polyprotein
(Human immunodeficiency virus type 1 group M subtyp...) | BDBM32049
(4-[[2-amino-3-(3-chlorophenyl)sulfonyl-4,9-dihydro...)Show SMILES Nc1c(c2Nc3ccccc3Nc2n1N=CC1=CC(=O)C(=O)C=C1)S(=O)(=O)c1cccc(Cl)c1 |w:14.16,c:25,t:19| Show InChI InChI=1S/C23H16ClN5O4S/c24-14-4-3-5-15(11-14)34(32,33)21-20-23(28-17-7-2-1-6-16(17)27-20)29(22(21)25)26-12-13-8-9-18(30)19(31)10-13/h1-12,27-28H,25H2 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | 266 | n/a | n/a | n/a | n/a | 8.0 | 23 |
University of Pittsburgh Molecular Library Screening Center
Curated by PubChem BioAssay
| Assay Description
A fluorescence resonance energy transfer assay is developed in 96-well and 384-well microplate formats with robotic manipulation to enable high-throu... |
PubChem Bioassay (2007)
BindingDB Entry DOI: 10.7270/Q2H70D5W |
More data for this
Ligand-Target Pair | |
DNA damage-inducible transcript 3 protein
(Mus musculus) | BDBM32049
(4-[[2-amino-3-(3-chlorophenyl)sulfonyl-4,9-dihydro...)Show SMILES Nc1c(c2Nc3ccccc3Nc2n1N=CC1=CC(=O)C(=O)C=C1)S(=O)(=O)c1cccc(Cl)c1 |w:14.16,c:25,t:19| Show InChI InChI=1S/C23H16ClN5O4S/c24-14-4-3-5-15(11-14)34(32,33)21-20-23(28-17-7-2-1-6-16(17)27-20)29(22(21)25)26-12-13-8-9-18(30)19(31)10-13/h1-12,27-28H,25H2 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description
NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q28C9TQN |
More data for this
Ligand-Target Pair | |
DNA damage-inducible transcript 3 protein
(Mus musculus) | BDBM32049
(4-[[2-amino-3-(3-chlorophenyl)sulfonyl-4,9-dihydro...)Show SMILES Nc1c(c2Nc3ccccc3Nc2n1N=CC1=CC(=O)C(=O)C=C1)S(=O)(=O)c1cccc(Cl)c1 |w:14.16,c:25,t:19| Show InChI InChI=1S/C23H16ClN5O4S/c24-14-4-3-5-15(11-14)34(32,33)21-20-23(28-17-7-2-1-6-16(17)27-20)29(22(21)25)26-12-13-8-9-18(30)19(31)10-13/h1-12,27-28H,25H2 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description
NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q2PC30VZ |
More data for this
Ligand-Target Pair | |
X-box-binding protein 1
(Homo sapiens (Human)) | BDBM32049
(4-[[2-amino-3-(3-chlorophenyl)sulfonyl-4,9-dihydro...)Show SMILES Nc1c(c2Nc3ccccc3Nc2n1N=CC1=CC(=O)C(=O)C=C1)S(=O)(=O)c1cccc(Cl)c1 |w:14.16,c:25,t:19| Show InChI InChI=1S/C23H16ClN5O4S/c24-14-4-3-5-15(11-14)34(32,33)21-20-23(28-17-7-2-1-6-16(17)27-20)29(22(21)25)26-12-13-8-9-18(30)19(31)10-13/h1-12,27-28H,25H2 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description
NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q2NK3CGB |
More data for this
Ligand-Target Pair | |
Heat shock protein HSP 90-alpha
(Homo sapiens (Human)) | BDBM32049
(4-[[2-amino-3-(3-chlorophenyl)sulfonyl-4,9-dihydro...)Show SMILES Nc1c(c2Nc3ccccc3Nc2n1N=CC1=CC(=O)C(=O)C=C1)S(=O)(=O)c1cccc(Cl)c1 |w:14.16,c:25,t:19| Show InChI InChI=1S/C23H16ClN5O4S/c24-14-4-3-5-15(11-14)34(32,33)21-20-23(28-17-7-2-1-6-16(17)27-20)29(22(21)25)26-12-13-8-9-18(30)19(31)10-13/h1-12,27-28H,25H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description
A fluorescence polarization based HTS assay has been developed and optimized for the identification of Hsp90 inhibitors by using tumor cell lysate Hs... |
PubChem Bioassay (2007)
BindingDB Entry DOI: 10.7270/Q2Q23XM6 |
More data for this
Ligand-Target Pair | |
cAMP-dependent protein kinase catalytic subunit alpha
(Homo sapiens (Human)) | BDBM32049
(4-[[2-amino-3-(3-chlorophenyl)sulfonyl-4,9-dihydro...)Show SMILES Nc1c(c2Nc3ccccc3Nc2n1N=CC1=CC(=O)C(=O)C=C1)S(=O)(=O)c1cccc(Cl)c1 |w:14.16,c:25,t:19| Show InChI InChI=1S/C23H16ClN5O4S/c24-14-4-3-5-15(11-14)34(32,33)21-20-23(28-17-7-2-1-6-16(17)27-20)29(22(21)25)26-12-13-8-9-18(30)19(31)10-13/h1-12,27-28H,25H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | >5.96E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... |
PubChem Bioassay (2007)
BindingDB Entry DOI: 10.7270/Q24X565S |
More data for this
Ligand-Target Pair | |
ATP-dependent molecular chaperone HSP82
(Candida albicans) | BDBM32049
(4-[[2-amino-3-(3-chlorophenyl)sulfonyl-4,9-dihydro...)Show SMILES Nc1c(c2Nc3ccccc3Nc2n1N=CC1=CC(=O)C(=O)C=C1)S(=O)(=O)c1cccc(Cl)c1 |w:14.16,c:25,t:19| Show InChI InChI=1S/C23H16ClN5O4S/c24-14-4-3-5-15(11-14)34(32,33)21-20-23(28-17-7-2-1-6-16(17)27-20)29(22(21)25)26-12-13-8-9-18(30)19(31)10-13/h1-12,27-28H,25H2 | PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | n/a | n/a | 6.49E+3 | n/a | n/a | n/a | n/a |
Broad Institute
Curated by PubChem BioAssay
| Assay Description
Broad Institute: Reversing Antifungal Drug Resistance Project ID: 2037 Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, Calcineurin, ... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q26M358G |
More data for this
Ligand-Target Pair | |