Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 522.3 BDBM50365017

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM50365017 (CHEMBL1950785) Show SMILES Nc1cc(cnc1N1CCC[C@H]1c1nc2cc(Cl)c(Cl)cc2[nH]1)-c1ccc(OCC(F)(F)F)cc1 |r| Show InChI InChI=1S/C24H20Cl2F3N5O/c25-16-9-19-20(10-17(16)26)33-22(32-19)21-2-1-7-34(21)23-18(30)8-14(11-31-23)13-3-5-15(6-4-13)35-12-24(27,28)29/h3-6,8-11,21H,1-2,7,12,30H2,(H,32,33)/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate after 30 mins by fluorescence analysis				Bioorg Med Chem Lett 22: 1727-30 (2012) Article DOI: 10.1016/j.bmcl.2011.12.098 BindingDB Entry DOI: 10.7270/Q2GT5NNH
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