Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Arachidonate 5-lipoxygenase-activating protein
(Homo sapiens (Human)) | BDBM166974
(US9073876, 60 | US9732093, Compound 60)Show SMILES Nc1cnc(cn1)-c1ccc(C2CCC2)c(OCC(O)Cn2cccn2)c1F Show InChI InChI=1S/C20H22FN5O2/c21-19-16(17-9-24-18(22)10-23-17)6-5-15(13-3-1-4-13)20(19)28-12-14(27)11-26-8-2-7-25-26/h2,5-10,13-14,27H,1,3-4,11-12H2,(H2,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| 116 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
JANSSEN PHARMACEUTICA NV
US Patent
| Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai... |
US Patent US9073876 (2015)
BindingDB Entry DOI: 10.7270/Q28S4NPC |
More data for this
Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM166974
(US9073876, 60 | US9732093, Compound 60)Show SMILES Nc1cnc(cn1)-c1ccc(C2CCC2)c(OCC(O)Cn2cccn2)c1F Show InChI InChI=1S/C20H22FN5O2/c21-19-16(17-9-24-18(22)10-23-17)6-5-15(13-3-1-4-13)20(19)28-12-14(27)11-26-8-2-7-25-26/h2,5-10,13-14,27H,1,3-4,11-12H2,(H2,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| 116 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
JANSSEN PHARMACEUTICA NV
US Patent
| Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai... |
US Patent US9732093 (2017)
BindingDB Entry DOI: 10.7270/Q2NV9MCX |
More data for this
Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM166974
(US9073876, 60 | US9732093, Compound 60)Show SMILES Nc1cnc(cn1)-c1ccc(C2CCC2)c(OCC(O)Cn2cccn2)c1F Show InChI InChI=1S/C20H22FN5O2/c21-19-16(17-9-24-18(22)10-23-17)6-5-15(13-3-1-4-13)20(19)28-12-14(27)11-26-8-2-7-25-26/h2,5-10,13-14,27H,1,3-4,11-12H2,(H2,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| 116 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
JANSSEN PHARMACEUTICA NV
US Patent
| Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai... |
US Patent US9732093 (2017)
BindingDB Entry DOI: 10.7270/Q2NV9MCX |
More data for this
Ligand-Target Pair | |