Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Phosphatidylinositol 3-kinase catalytic subunit type 3
(Homo sapiens (Human)) | BDBM338056
(US9751854, Compound I-231 | US9802960, Compound I-...)Show InChI InChI=1S/C10H10N4/c11-9-3-8(5-13-6-9)7-1-2-14-10(12)4-7/h1-6H,11H2,(H2,12,14) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc.
US Patent
| Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro... |
US Patent US9802960 (2017)
BindingDB Entry DOI: 10.7270/Q2D79DJ9 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 3-kinase catalytic subunit type 3
(Homo sapiens (Human)) | BDBM338056
(US9751854, Compound I-231 | US9802960, Compound I-...)Show InChI InChI=1S/C10H10N4/c11-9-3-8(5-13-6-9)7-1-2-14-10(12)4-7/h1-6H,11H2,(H2,12,14) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc.
US Patent
| Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro... |
US Patent US9751854 (2017)
BindingDB Entry DOI: 10.7270/Q2KS6TNJ |
More data for this Ligand-Target Pair | |