Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 278.1 BDBM50215930

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage metalloelastase (Homo sapiens (Human))	BDBM50215930 (4-(5-bromo-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridi...) Show SMILES Nc1nc2c(nccc2[nH]1)-c1ccc(Br)[nH]1 Show InChI InChI=1S/C10H8BrN5/c11-7-2-1-5(14-7)8-9-6(3-4-13-8)15-10(12)16-9/h1-4,14H,(H3,12,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human MMP12 catalytic domain				Bioorg Med Chem Lett 19: 5461-3 (2009) Article DOI: 10.1016/j.bmcl.2009.07.099 BindingDB Entry DOI: 10.7270/Q2HX1CRC
					More data for this Ligand-Target Pair
Macrophage metalloelastase (Homo sapiens (Human))	BDBM50215930 (4-(5-bromo-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridi...) Show SMILES Nc1nc2c(nccc2[nH]1)-c1ccc(Br)[nH]1 Show InChI InChI=1S/C10H8BrN5/c11-7-2-1-5(14-7)8-9-6(3-4-13-8)15-10(12)16-9/h1-4,14H,(H3,12,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Co. Ltd Curated by ChEMBL					Assay Description Inhibition of MMP12				Bioorg Med Chem Lett 17: 4495-9 (2007) Article DOI: 10.1016/j.bmcl.2007.06.005 BindingDB Entry DOI: 10.7270/Q2MW2GVX
					More data for this Ligand-Target Pair