Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50347813
(CHEMBL1802393)Show SMILES Nc1ncc(-c2ccc(cc2)C(F)(F)F)c(n1)-c1c[nH]c2ccc(Br)cc12 Show InChI InChI=1S/C19H12BrF3N4/c20-12-5-6-16-13(7-12)15(9-25-16)17-14(8-26-18(24)27-17)10-1-3-11(4-2-10)19(21,22)23/h1-9,25H,(H2,24,26,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Clermont Universite£
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant GST-tagged CLK1 using GRSRSRSRSRSR as substrate |
J Med Chem 54: 4474-89 (2011)
Article DOI: 10.1021/jm200464w
BindingDB Entry DOI: 10.7270/Q2ZW1M8P |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50347813
(CHEMBL1802393)Show SMILES Nc1ncc(-c2ccc(cc2)C(F)(F)F)c(n1)-c1c[nH]c2ccc(Br)cc12 Show InChI InChI=1S/C19H12BrF3N4/c20-12-5-6-16-13(7-12)15(9-25-16)17-14(8-26-18(24)27-17)10-1-3-11(4-2-10)19(21,22)23/h1-9,25H,(H2,24,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Clermont Universite£
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CDK5/p25 using Histone H1 and [gamma32]-ATP after 30 mins by scintillation counting |
J Med Chem 54: 4474-89 (2011)
Article DOI: 10.1021/jm200464w
BindingDB Entry DOI: 10.7270/Q2ZW1M8P |
More data for this
Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50347813
(CHEMBL1802393)Show SMILES Nc1ncc(-c2ccc(cc2)C(F)(F)F)c(n1)-c1c[nH]c2ccc(Br)cc12 Show InChI InChI=1S/C19H12BrF3N4/c20-12-5-6-16-13(7-12)15(9-25-16)17-14(8-26-18(24)27-17)10-1-3-11(4-2-10)19(21,22)23/h1-9,25H,(H2,24,26,27) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Clermont Universite£
Curated by ChEMBL
| Assay Description
Inhibition of rat recombinant GST-tagged DYRK1A using myelin protein as substrate and [gamma32]-ATP after 30 mins by scintillation counting |
J Med Chem 54: 4474-89 (2011)
Article DOI: 10.1021/jm200464w
BindingDB Entry DOI: 10.7270/Q2ZW1M8P |
More data for this
Ligand-Target Pair | |