Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Mitogen-activated protein kinase kinase kinase 12
(Homo sapiens (Human)) | BDBM289484
((4-(6-amino-5-(trifluoro- methyl)pyridin-3- yl)-1-...)Show SMILES Nc1ncc(cc1C(F)(F)F)-c1cn(c(n1)C(O)C1CC1)C12CC(C1)C2 Show InChI InChI=1S/C18H19F3N4O/c19-18(20,21)12-3-11(7-23-15(12)22)13-8-25(17-4-9(5-17)6-17)16(24-13)14(26)10-1-2-10/h3,7-10,14,26H,1-2,4-6H2,(H2,22,23) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System
US Patent
| Assay Description
The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... |
US Patent US10093664 (2018)
BindingDB Entry DOI: 10.7270/Q28P62KQ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase 12
(Homo sapiens (Human)) | BDBM289425
((R)-(4-(6-amino-5-(trifluoromethyl)pyridin-3-yl)-1...)Show SMILES Nc1ncc(cc1C(F)(F)F)-c1cn(c(n1)[C@H](O)C1CC1)C12CC(C1)C2 |r| Show InChI InChI=1S/C18H19F3N4O/c19-18(20,21)12-3-11(7-23-15(12)22)13-8-25(17-4-9(5-17)6-17)16(24-13)14(26)10-1-2-10/h3,7-10,14,26H,1-2,4-6H2,(H2,22,23)/t9?,14-,17?/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System
US Patent
| Assay Description
The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK... |
US Patent US10093664 (2018)
BindingDB Entry DOI: 10.7270/Q28P62KQ |
More data for this
Ligand-Target Pair | |