Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 425.4 BDBM289493

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human))	BDBM289493 ((4-(6-amino-5-(trifluoro- methoxy)pyridin-3- yl)-1...) Show SMILES Nc1ncc(cc1OC(F)(F)F)-c1cn(c(CO)n1)C12CC(C1)(C2)N1CCOCC1 Show InChI InChI=1S/C19H22F3N5O3/c20-19(21,22)30-14-5-12(6-24-16(14)23)13-7-27(15(8-28)25-13)18-9-17(10-18,11-18)26-1-3-29-4-2-26/h5-7,28H,1-4,8-11H2,(H2,23,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK...				US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ
					More data for this Ligand-Target Pair