Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 380.3 BDBM289480

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human))	BDBM289480 ((4-(6-amino-5-(tri- fluoromethoxy)pyridin- 3-yl)-1...) Show SMILES Nc1ncc(cc1OC(F)(F)F)-c1cn(c(n1)C(O)C1CC1)C12CC(C1)C2 Show InChI InChI=1S/C18H19F3N4O2/c19-18(20,21)27-13-3-11(7-23-15(13)22)12-8-25(17-4-9(5-17)6-17)16(24-12)14(26)10-1-2-10/h3,7-10,14,26H,1-2,4-6H2,(H2,22,23)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK...				US Patent US10093664 (2018) BindingDB Entry DOI: 10.7270/Q28P62KQ
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