Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 330.3 BDBM50182365

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50182365 (3-(2-aminopyrimidin-4-yl)-2-(4-fluorophenyl)H-imid...) Show SMILES Nc1nccc(n1)-c1c(nc2cc(ccn12)C#N)-c1ccc(F)cc1 Show InChI InChI=1S/C18H11FN6/c19-13-3-1-12(2-4-13)16-17(14-5-7-22-18(21)23-14)25-8-6-11(10-20)9-15(25)24-16/h1-9H,(H2,21,22,23)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11.3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against PKG				Bioorg Med Chem Lett 16: 2479-83 (2006) Article DOI: 10.1016/j.bmcl.2006.01.092 BindingDB Entry DOI: 10.7270/Q24X57CW
					More data for this Ligand-Target Pair