Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 509.8 BDBM487592

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM487592 (N-(4-(2-aminopyrimidin-4-yl)-3- chlorophenyl)-1-(i...) Show SMILES Nc1nccc(n1)-c1ccc(NC(=O)c2cnn(c2C(F)(F)F)-c2cccc3ccncc23)cc1Cl Show InChI InChI=1S/C24H15ClF3N7O/c25-18-10-14(4-5-15(18)19-7-9-31-23(29)34-19)33-22(36)17-12-32-35(21(17)24(26,27)28)20-3-1-2-13-6-8-30-11-16(13)20/h1-12H,(H,33,36)(H2,29,31,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...				US Patent US10954214 (2021) BindingDB Entry DOI: 10.7270/Q2SX6HB1
					More data for this Ligand-Target Pair