Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 499.8 BDBM487908

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM487908 (1-(1-aminoisoquinolin-5-yl)-N- (5-chloro-6-(2H-1,2...) Show SMILES Nc1nccc2c(cccc12)-n1ncc(C(=O)Nc2cnc(c(Cl)c2)-n2nccn2)c1C(F)(F)F Show InChI InChI=1S/C21H13ClF3N9O/c22-15-8-11(9-28-19(15)34-29-6-7-30-34)32-20(35)14-10-31-33(17(14)21(23,24)25)16-3-1-2-13-12(16)4-5-27-18(13)26/h1-10H,(H2,26,27)(H,32,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	646	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...				US Patent US10954214 (2021) BindingDB Entry DOI: 10.7270/Q2SX6HB1
					More data for this Ligand-Target Pair