Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 394.4 BDBM98332

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Activated CDC42 kinase 1 (Homo sapiens (Human))	BDBM98332 (US8481733, 144) Show SMILES Nc1nccn2c(nc(-c3ccc(Oc4ccccc4)cc3)c12)-c1cccc(O)c1 Show InChI InChI=1S/C24H18N4O2/c25-23-22-21(16-9-11-20(12-10-16)30-19-7-2-1-3-8-19)27-24(28(22)14-13-26-23)17-5-4-6-18(29)15-17/h1-15,29H,(H2,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	348	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, LLC US Patent					Assay Description AlphaScreen (amplified luminescent proximity homogeneous assay) assay was used to test for ACK1 inhibitory activity.				US Patent US8481733 (2013) BindingDB Entry DOI: 10.7270/Q2XD109J
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