Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 527.2 BDBM393714

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Homo sapiens (Human))	BDBM393714 ((R)—N-(1-(3-Amino-4-chloroisoxazolo[5,4-c]pyridin-...) Show SMILES Nc1noc2c(ncc(Cl)c12)N1CC[C@H](C1)NC(=O)c1ccc(cc1Cl)-n1cnnc1C(F)(F)F |r| Show InChI InChI=1S/C20H15Cl2F3N8O2/c21-12-5-10(33-8-28-30-19(33)20(23,24)25)1-2-11(12)18(34)29-9-3-4-32(7-9)17-15-14(13(22)6-27-17)16(26)31-35-15/h1-2,5-6,8-9H,3-4,7H2,(H2,26,31)(H,29,34)/t9-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...				J Med Chem 52: 2818-24 (2009) BindingDB Entry DOI: 10.7270/Q2WQ063R
					More data for this Ligand-Target Pair