Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50349669
(CHEMBL1809035)Show SMILES O=C([C@H]1CN([C@@H]2Cc3c[nH]c4cccc(C2=C1)c34)C(=O)c1ccccc1)N1CCCC1 |r,c:16| Show InChI InChI=1S/C26H25N3O2/c30-25(28-11-4-5-12-28)19-13-21-20-9-6-10-22-24(20)18(15-27-22)14-23(21)29(16-19)26(31)17-7-2-1-3-8-17/h1-3,6-10,13,15,19,23,27H,4-5,11-12,14,16H2/t19-,23-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Antagonist activity at human CXCR3 expressed in mouse L1.2 cells assessed as inhibition of ITAC-induced calcium mobilization by FLIPR assay |
Bioorg Med Chem Lett 21: 4745-9 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.070 BindingDB Entry DOI: 10.7270/Q2VM4CN5 |
More data for this Ligand-Target Pair | |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50349669
(CHEMBL1809035)Show SMILES O=C([C@H]1CN([C@@H]2Cc3c[nH]c4cccc(C2=C1)c34)C(=O)c1ccccc1)N1CCCC1 |r,c:16| Show InChI InChI=1S/C26H25N3O2/c30-25(28-11-4-5-12-28)19-13-21-20-9-6-10-22-24(20)18(15-27-22)14-23(21)29(16-19)26(31)17-7-2-1-3-8-17/h1-3,6-10,13,15,19,23,27H,4-5,11-12,14,16H2/t19-,23-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description Displacement of radiolabeled CXCL11 from human CXCR3 expressed in CHO cells by scintillation proximity assay |
Bioorg Med Chem Lett 21: 4745-9 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.070 BindingDB Entry DOI: 10.7270/Q2VM4CN5 |
More data for this Ligand-Target Pair | |