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Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 379.4
BDBM50021391

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50021391 (CHEMBL3289596) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Braunschweig Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK2/cyclin E				Eur J Med Chem 83: 274-83 (2014) Article DOI: 10.1016/j.ejmech.2014.06.020 BindingDB Entry DOI: 10.7270/Q2WW7K8X
Technische Universit£t Braunschweig Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50021391 (CHEMBL3289596) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Braunschweig Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25				Eur J Med Chem 83: 274-83 (2014) Article DOI: 10.1016/j.ejmech.2014.06.020 BindingDB Entry DOI: 10.7270/Q2WW7K8X
Technische Universit£t Braunschweig Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50021391 (CHEMBL3289596) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Braunschweig Curated by ChEMBL					Assay Description Inhibition of human recombinant DYRK1A				Eur J Med Chem 83: 274-83 (2014) Article DOI: 10.1016/j.ejmech.2014.06.020 BindingDB Entry DOI: 10.7270/Q2WW7K8X
Technische Universit£t Braunschweig Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Mus musculus)	BDBM50021391 (CHEMBL3289596) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Braunschweig Curated by ChEMBL					Assay Description Inhibition of mouse recombinant CLK1				Eur J Med Chem 83: 274-83 (2014) Article DOI: 10.1016/j.ejmech.2014.06.020 BindingDB Entry DOI: 10.7270/Q2WW7K8X
Technische Universit£t Braunschweig Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-T1/Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM50021391 (CHEMBL3289596) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Braunschweig Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK9/cyclin T				Eur J Med Chem 83: 274-83 (2014) Article DOI: 10.1016/j.ejmech.2014.06.020 BindingDB Entry DOI: 10.7270/Q2WW7K8X
Technische Universit£t Braunschweig Curated by ChEMBL					More data for this Ligand-Target Pair