Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140476
((E)-N-(1-Benzyl-piperidin-4-yl)-N-(2-oxo-2,3-dihyd...)Show SMILES O=C(\C=C\c1ccccc1)N(C1CCN(Cc2ccccc2)CC1)c1ccc2CC(=O)Nc2c1 Show InChI InChI=1S/C29H29N3O2/c33-28-19-24-12-13-26(20-27(24)30-28)32(29(34)14-11-22-7-3-1-4-8-22)25-15-17-31(18-16-25)21-23-9-5-2-6-10-23/h1-14,20,25H,15-19,21H2,(H,30,33)/b14-11+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY from human NPYY2 receptor |
Bioorg Med Chem Lett 24: 430-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.061
BindingDB Entry DOI: 10.7270/Q2H133HQ |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140476
((E)-N-(1-Benzyl-piperidin-4-yl)-N-(2-oxo-2,3-dihyd...)Show SMILES O=C(\C=C\c1ccccc1)N(C1CCN(Cc2ccccc2)CC1)c1ccc2CC(=O)Nc2c1 Show InChI InChI=1S/C29H29N3O2/c33-28-19-24-12-13-26(20-27(24)30-28)32(29(34)14-11-22-7-3-1-4-8-22)25-15-17-31(18-16-25)21-23-9-5-2-6-10-23/h1-14,20,25H,15-19,21H2,(H,30,33)/b14-11+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057
BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this
Ligand-Target Pair | |